Dr. McDreamy is shirtless! Patrick Dempsey, known as Dr. Derek Shepard in Grey’s Anatomy is on the cover of Entertainment Weekly’s annual photo issue. The magazine issue is said to have a 10-page portfolio of Dr. McDreamy and I think that’s enough to make the girls go crazy. Here’s some interview snippets:

On his metamorphosis from McDorky to McDreamy in 1999: ‘’I went and did other things, like starting a relationship that was loving and nurturing (his marriage to makeup artist Jillian Fink).”

On his upcoming Disney comedy-fantasy-musical film: ‘’There’s nothing wrong with making a commercial movie if you’re telling a good story. Enchanted felt like the right movie to make. With all the violence in the world, it provides a nice escape. I don’t like pretentious movies. We’re entertainers. We’re not saving lives.’’

Entertainment Weekly’s annual photo issue hits newsstands nationwide Monday!

+ Patrick Dempsey looks cute in a pink dress

More McDreaminess after the jump.